Urticaria causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]


Urticaria may be caused idiopathically or due to immunological disorders such as autoimmune diseases, food allergies, medications and specific infections. There are also some non-immunological causes for urticaria development, such as physical triggers, dietary pseudo-allergen and hereditary urticaria.


Common Causes

Common causes of urticaria may include:[1][2][3][4]

The items:

High frequency of cross-reactivity, such as avocado, banana and chestnut
Moderate frequency of cross-reactivity such as apple, carrot, celery, kiwi, melon, papaya, potato and tomato
Low frequency of cross-reactivity, such as apricot, cherry, fig, grape, hazelnut, mango, nectarine, passion fruit, peach, peanut, pear, plum, pineapple, soybean, strawberry and walnut.



  1. 1.0 1.1 1.2 Deacock SJ (2008). "An approach to the patient with urticaria". Clin Exp Immunol. 153 (2): 151–61. doi:10.1111/j.1365-2249.2008.03693.x. PMC 2492902. PMID 18713139.
  2. Erben AM, Rodriguez JL, McCullough J, Ownby DR (1993). "Anaphylaxis after ingestion of beignets contaminated with Dermatophagoides farinae". J Allergy Clin Immunol. 92 (6): 846–9. doi:10.1016/0091-6749(93)90062-k. PMID 8258619.
  3. Beezhold DH, Sussman GL, Liss GM, Chang NS (1996). "Latex allergy can induce clinical reactions to specific foods". Clin Exp Allergy. 26 (4): 416–22. PMID 8732238.
  4. 4.0 4.1 4.2 4.3 4.4 Kayiran MA, Akdeniz N (2019). "Diagnosis and treatment of urticaria in primary care". North Clin Istanb. 6 (1): 93–99. doi:10.14744/nci.2018.75010. PMC 6526977 Check |pmc= value (help). PMID 31180381.
  5. Rajan JP, Simon RA, Bosso JV (2014). "Prevalence of sensitivity to food and drug additives in patients with chronic idiopathic urticaria". J Allergy Clin Immunol Pract. 2 (2): 168–71. doi:10.1016/j.jaip.2013.10.002. PMID 24607044.
  6. Wedi B, Kapp A (1999). "Helicobacter pylori infection and skin diseases". J Physiol Pharmacol. 50 (5): 753–76. PMID 10695557.
  7. Akashi R, Ishiguro N, Shimizu S, Kawashima M (2011). "Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori". J Dermatol. 38 (8): 761–6. doi:10.1111/j.1346-8138.2010.01106.x. PMID 21352335.
  8. Karaman U, Sener S, Calık S, Saşmaz S (2011). "[Investigation of microsporidia in patients with acute and chronic urticaria]". Mikrobiyol Bul. 45 (1): 168–73. PMID 21341171.
  9. 9.0 9.1 Zuberbier T (2003). "Urticaria". Allergy. 58 (12): 1224–34. doi:10.1046/j.1398-9995.2003.00327.x. PMID 14616095.
  10. Ros AM, Juhlin L, Michaëlsson G (1976). "A follow-up study of patients with recurrent urticaria and hypersensitivity to aspirin, benzoates and azo dyes". Br J Dermatol. 95 (1): 19–24. doi:10.1111/j.1365-2133.1976.tb15532.x. PMID 952737.
  11. Morrow JD, Margolies GR, Rowland J, Roberts LJ (1991). "Evidence that histamine is the causative toxin of scombroid-fish poisoning". N Engl J Med. 324 (11): 716–20. doi:10.1056/NEJM199103143241102. PMID 1997836.
  12. Zuberbier T, Iffländer J, Semmler C, Henz BM (1996). "Acute urticaria: clinical aspects and therapeutic responsiveness". Acta Derm Venereol. 76 (4): 295–7. doi:10.2340/0001555576295297. PMID 8869688.
  13. Soter NA, Joshi NP, Twarog FJ, Zeiger RS, Rothman PM, Colten HR (1977). "Delayed cold-induced urticaria: a dominantly inherited disorder". J Allergy Clin Immunol. 59 (4): 294–7. doi:10.1016/0091-6749(77)90050-1. PMID 66242.
  14. Staubach P, Dechene M, Metz M, Magerl M, Siebenhaar F, Weller K; et al. (2011). "High prevalence of mental disorders and emotional distress in patients with chronic spontaneous urticaria". Acta Derm Venereol. 91 (5): 557–61. doi:10.2340/00015555-1109. PMID 21597672.

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