Lymphadenopathy natural history, complications and prognosis
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The natural course of lymphadenopathy depends on the underlying cause. Lymphadenopathy due to infectious causes subsides once the infection is controlled. Common complications of lymphadenopathy depend on the site of involvement, e.g. mediastinal lymphadenopathy include compression symptoms like Tracheal and bronchial obstruction and Dysphagia in Superior vena cava syndrome. Prognosis is generally excellent for infectious causes. Prompt treatment with antibiotics usually leads to a complete recovery. However, it may take weeks, or even months, for swelling to disappear. The amount of time to recovery depends on the cause. Prognosis is poor for malignant tumors.
Natural History, Complications and Prognosis
- Patients with lymphadenopathy may be symptomatic or asymptomatic, depending on the etiology.
- Early clinical features include palpable tenderness, pain, and fever.
- Common complications of mediastinal lymphadenopathy include:
- Uric acid nephropathy
- Renal failure
- Abdominal lymphadenopathy may cause following complications:
- Complications of superficial lymphadenopathy include:
Prompt treatment with antibiotics usually leads to a complete recovery. However, it may take weeks, or even months, for swelling to disappear. The amount of time to recovery depends on the cause. Prognosis is poor for malignant tumors.
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