Cirrhosis secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Sudarshana Datta, MD [3]


Secondary prevention in patients with cirrhosis is aimed at preventing further damage to the liver. Avoidance of alcohol and other hepatotoxins, treatment of underlying chronic liver disease and immunization against viral hepatitis for susceptible patients are key measures of secondary prevention of cirrhosis.

Secondary Prevention


  1. Lewis JH, Stine JG (2013). "Review article: prescribing medications in patients with cirrhosis - a practical guide". Aliment. Pharmacol. Ther. 37 (12): 1132–56. doi:10.1111/apt.12324. PMID 23638982.
  2. Borowsky SA, Strome S, Lott E (1981). "Continued heavy drinking and survival in alcoholic cirrhotics". Gastroenterology. 80 (6): 1405–9. PMID 6971772.
  3. Pessione F, Ramond MJ, Peters L, Pham BN, Batel P, Rueff B, Valla DC (2003). "Five-year survival predictive factors in patients with excessive alcohol intake and cirrhosis. Effect of alcoholic hepatitis, smoking and abstinence". Liver Int. 23 (1): 45–53. PMID 12640727.
  4. Alvarez MA, Cirera I, Solà R, Bargalló A, Morillas RM, Planas R (2011). "Long-term clinical course of decompensated alcoholic cirrhosis: a prospective study of 165 patients". J. Clin. Gastroenterol. 45 (10): 906–11. doi:10.1097/MCG.0b013e3182284e13. PMID 21814145.
  5. Brunt PW, Kew MC, Scheuer PJ, Sherlock S (1974). "Studies in alcoholic liver disease in Britain. I. Clinical and pathological patterns related to natural history". Gut. 15 (1): 52–8. PMC 1412935. PMID 4362373.
  6. Luca A, García-Pagán JC, Bosch J, Feu F, Caballería J, Groszmann RJ, Rodés J (1997). "Effects of ethanol consumption on hepatic hemodynamics in patients with alcoholic cirrhosis". Gastroenterology. 112 (4): 1284–9. PMID 9098014.

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