Aminopropionitrile
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Names | |
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IUPAC name
3-Aminopropanenitrile[1]
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Other names
2-Cyanoethylamine[citation needed]
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
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KEGG | |
MeSH | Aminopropionitrile |
PubChem CID
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Properties | |
C3H6N2 | |
Molar mass | 70.10 g·mol−1 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is an antirheumatic agent in veterinary medicine. It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism.[2]
Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.[3]
BAPN is a component of lathyrus odoratus.[4]
See also
References
- ↑ "Aminopropionitrile - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Retrieved 7 June 2012.
- ↑ Nikolaos Papadantonakis, Shinobu Matsuura, and Katya Ravid. "Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection". Blood. 120 (9): 1774–1781. doi:10.1182/blood-2012-02-402594.
BAPN is a lathyrogen, the toxic constituent of peas from Lathyrus plants. Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of the nervous system (neurolathyrism) leading to limb paralysis, and a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities.
- ↑ Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001
- ↑ "Lathyrus". Washington, DC: American Association for Clinical Chemistry. 2014. Retrieved 15 October 2014.
Beta-amino-propionitrile (BAPN) found in lathyrus odoratus (our more common garden sweet pea plant) is thought to be responsible for osteolathyrism, which in humans is quite poorly documented.
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